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Chromatin remodelers, their implication in cancer and therapeutic potential

Manelyte, Laura (2017) Chromatin remodelers, their implication in cancer and therapeutic potential. Journal of Rare Diseases Research & Treatment 2 (3), pp. 34-40.

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Date of publication of this fulltext: 04 Dec 2017 15:38

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Other URL: http://www.rarediseasesjournal.com/articles/chromatin-remodelers-their-implication-in-cancer-and-therapeutic-potential.html


Abstract

The chromatin remodeling complexes alter chromatin structures. They remodel nucleosomes in ATP-dependent manner and have essential roles in DNA damage repair, recombination, replication and transcriptional control. Increasing evidences indicate that subunits of chromatin remodelers are mutated and/or deregulated in a number of human cancers, and how they influence the cancer gene expression ...

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Item type:Article
Date:10 May 2017
Institutions:Biology, Preclinical Medicine > Institut für Biochemie, Genetik und Mikrobiologie > Lehrstuhl für Biochemie III > House of the Ribosome
Projects:Open Access Publizieren (DFG)
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ValueType
keine DOI angegebenDOI
Keywords:Chromatin remodeler; Cancer; Epigenetic therapeutic potential
Dewey Decimal Classification:500 Science > 570 Life sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:36405
Owner only: item control page

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