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Expanding the Scope of Impedance Spectroscopy for the Analysis of Adherent Cells: Electrode Material, Electrode Design, and Data Analysis

Götz, Christian (2018) Expanding the Scope of Impedance Spectroscopy for the Analysis of Adherent Cells: Electrode Material, Electrode Design, and Data Analysis. PhD, Universität Regensburg.

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Date of publication of this fulltext: 16 Oct 2018 07:25

Abstract (English)

This thesis focused on the advancement of impedance-based cellular assays using the electric cell-substrate impedance sensing (ECIS) approach. Three linchpins of ECIS were addressed: electrode material, electrode design, and data analysis. Typically, ECIS measurements are performed by application of ac currents with low amplitude between coplanar gold-film electrodes with adherent cell monolayers ...

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Translation of the abstract (German)

Das Ziel dieser Arbeit war die Weiterentwicklung der impedimetrischer Verfahren zur Analyse lebender adhärenter Zellen in vitro mittels Electric Cell-Substrate Impedance Sensing (ECIS). Dabei standen drei zentrale Themenbereiche dieses Ansatzes im Fokus: das verwendete Elektrodenmaterial, das Elektrodendesign und die Datenanalyse. Typischerweise werden ECIS-Messungen durch Anlegen niedriger ...

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Item type:Thesis of the University of Regensburg (PhD)
Date:16 October 2018
Referee:Prof. Dr. Joachim Wegener
Date of exam:5 December 2017
Institutions:Chemistry and Pharmacy > Institut für Analytische Chemie, Chemo- und Biosensorik
Chemistry and Pharmacy > Institut für Analytische Chemie, Chemo- und Biosensorik > Bioanalytik und Biosensorik (Prof. Joachim Wegener)
Keywords:Impedanzsspektroskopie, leitfähige Polymere, bipolare Elektroden, Derivativimpedanzspektroskopie, Zellanalyse, ECIS
Dewey Decimal Classification:500 Science > 500 Natural sciences & mathematics
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:36422
Owner only: item control page

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