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Pharmacological and Chemogenetic Characterization and Modulation of the Brain Neuropeptide S and Oxytocin

Grund, Thomas (2017) Pharmacological and Chemogenetic Characterization and Modulation of the Brain Neuropeptide S and Oxytocin. PhD, Universität Regensburg.

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Date of publication of this fulltext: 14 Dec 2017 09:28

Abstract (English)

Anxiety is a natural response to a real or perceived threat that has been conserved throughout evolution. From this perspective, sensation of anxiety is viewed as an adaptive behavioral state, which occurs in response to signals of danger. However, excessive or inappropriate anxiety can become pathological. Anxiety disorders represent one major burden of our modern society, and the available ...

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Translation of the abstract (German)

Aus evolutionsbiologischer Sicht ist Angst eine konservierte, natürliche Reaktion auf eine reale oder gefühlte Bedrohung. Allerdings können exzessive bzw. unangepasste Angstzustände ein pathologisches Ausmaß annehmen. Angsterkrankungen repräsentieren daher eine der Hauptbelastungen unserer modernen Gesellschaft. Da die derzeitigen Behandlungsmethoden limitiert und von Nebenwirkungen geprägt sind, ...

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Item type:Thesis of the University of Regensburg (PhD)
Date:14 December 2017
Referee:Prof. Dr. rer Inga Neumann
Date of exam:8 December 2017
Institutions:Biology, Preclinical Medicine > Institut für Zoologie > Tierphysiologie/Neurobiologie (Prof. Dr. Inga Neumann)
Keywords:neuropeptides, DREADD, NPS, oxytocin, anxiety, signaling, GCAMP6s, FACS, microdialysis
Dewey Decimal Classification:500 Science > 590 Zoological sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:36458
Owner only: item control page

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