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Götz, Th. I. ; Lahmer, G. ; Strnad, V. ; Bert, Ch. ; Hensel, B. ; Tomé, A. M. ; Lang, E. W.

A tool to automatically analyze electromagnetic tracking data from high dose rate brachytherapy of breast cancer patients

Götz, Th. I., Lahmer, G., Strnad, V., Bert, Ch., Hensel, B., Tomé, A. M. und Lang, E. W. (2017) A tool to automatically analyze electromagnetic tracking data from high dose rate brachytherapy of breast cancer patients. PLOS ONE 12 (9), e0183608.

Veröffentlichungsdatum dieses Volltextes: 22 Jan 2018 10:54
Artikel
DOI zum Zitieren dieses Dokuments: 10.5283/epub.36544


Zusammenfassung

During High Dose Rate Brachytherapy (HDR-BT) the spatial position of the radiation source inside catheters implanted into a female breast is determined via electromagnetic tracking (EMT). Dwell positions and dwell times of the radiation source are established, relative to the patient's anatomy, from an initial X-ray-CT-image. During the irradiation treatment, catheter displacements can occur due ...

During High Dose Rate Brachytherapy (HDR-BT) the spatial position of the radiation source inside catheters implanted into a female breast is determined via electromagnetic tracking (EMT). Dwell positions and dwell times of the radiation source are established, relative to the patient's anatomy, from an initial X-ray-CT-image. During the irradiation treatment, catheter displacements can occur due to patient movements. The current study develops an automatic analysis tool of EMT data sets recorded with a solenoid sensor to assure concordance of the source movement with the treatment plan. The tool combines machine learning techniques such as multi-dimensional scaling (MDS), ensemble empirical mode decomposition (EEMD), singular spectrum analysis (SSA) and particle filter (PF) to precisely detect and quantify any mismatch between the treatment plan and actual EMT measurements. We demonstrate that movement artifacts as well as technical signal distortions can be removed automatically and reliably, resulting in artifact-free reconstructed signals. This is a prerequisite for a highly accurate determination of any deviations of dwell positions from the treatment plan.



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Details

DokumentenartArtikel
Titel eines Journals oder einer ZeitschriftPLOS ONE
Verlag:PLOS
Ort der Veröffentlichung:SAN FRANCISCO
Band:12
Nummer des Zeitschriftenheftes oder des Kapitels:9
Seitenbereich:e0183608
Datum21 September 2017
InstitutionenBiologie und Vorklinische Medizin > Institut für Biophysik und physikalische Biochemie
Biologie und Vorklinische Medizin > Institut für Biophysik und physikalische Biochemie > Prof. Dr. Elmar Lang
Identifikationsnummer
WertTyp
10.1371/journal.pone.0183608DOI
Stichwörter / KeywordsEMPIRICAL MODE DECOMPOSITION; SINGULAR-SPECTRUM ANALYSIS; INTERSTITIAL BRACHYTHERAPY; SIMULTANEOUS LOCALIZATION; MUTUAL-INFORMATION; TIME-SERIES; DYNAMICS; IRRADIATION; PEARSONS; PROSTATE;
Dewey-Dezimal-Klassifikation500 Naturwissenschaften und Mathematik > 570 Biowissenschaften, Biologie
StatusVeröffentlicht
BegutachtetJa, diese Version wurde begutachtet
An der Universität Regensburg entstandenJa
URN der UB Regensburgurn:nbn:de:bvb:355-epub-365444
Dokumenten-ID36544

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