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BMP-7 Preserves Surface Integrity of Degradable-ceramic Cranioplasty in a Göttingen Minipig Model

URN to cite this document:
urn:nbn:de:bvb:355-epub-365884
DOI to cite this document:
10.5283/epub.36588
Roldán, J. Camilo ; Schulz, Peter ; Klünter, Tim ; Deisinger, Ulrike ; Diez, Claudius ; Waiss, Waltraud ; Kirschneck, Christian ; Reichert, Torsten E. ; Detsch, Rainer
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Date of publication of this fulltext: 25 Jan 2018 15:57


Abstract

Background: The aim of the study was to evaluate the integrity of a craniotomy grafted site in a minipig model using different highly porous calcium phosphate ceramic scaffolds either loaded or nonloaded with bone morphogenetic protein-7 (BMP-7). Methods: Four craniotomies with a diameter of 15 mm (critical-size defect) were grafted with different highly porous (92–94 vol%) calcium phosphate ...

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