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The presence of PD-1 positive tumor infiltrating lymphocytes in triple negative breast cancers is associated with a favorable outcome of disease

Brockhoff, Gero, Seitz, Stephan, Weber, Florian, Zeman, Florian, Klinkhammer-Schalke, Monika, Ortmann, Olaf and Kathrin Wege, Anja (2017) The presence of PD-1 positive tumor infiltrating lymphocytes in triple negative breast cancers is associated with a favorable outcome of disease. Oncotarget 2018 (9), pp. 6201-6212.

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Date of publication of this fulltext: 26 Jan 2018 14:33

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Other URL: http://doi.org/10.18632/oncotarget.23717, http://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=view&path[]=23717


Abstract

Triple negative breast cancer patients have a poor course of disease not least because of limited treatment options however immunotherapy by targeting the PD-1/PD-L1 checkpoint system is a promising strategy to improve the outcome. Here we systematically investigated the expression of PD-1 on tumor infiltrating lymphocytes and PD-L1 on both tumor and infiltrated immune cells. Moreover, the PD-L1 ...

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Item type:Article
Date:27 December 2017
Institutions:Medicine > Lehrstuhl für Frauenheilkunde und Geburtshilfe (Schwerpunkt Frauenheilkunde)
Projects:Open Access Publizieren (DFG)
Identification Number:
ValueType
10.18632/oncotarget.23717DOI
Keywords:triple negative breast cancer (TNBC); PD-(L)1
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:36618
Owner only: item control page

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