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Do Neuroendocrine Peptides and Their Receptors Qualify as Novel Therapeutic Targets in Osteoarthritis?

Grässel, Susanne and Muschter, Dominique (2018) Do Neuroendocrine Peptides and Their Receptors Qualify as Novel Therapeutic Targets in Osteoarthritis? International Journal of Molecular Sciences 19 (2), p. 367.

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Date of publication of this fulltext: 05 Mar 2018 16:58

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Other URL: http://doi.org/10.3390/ijms19020367, http://www.mdpi.com/1422-0067/19/2/367


Abstract

Joint tissues like synovium, articular cartilage, meniscus and subchondral bone, are targets for neuropeptides. Resident cells of these tissues express receptors for various neuroendocrine-derived peptides including proopiomelanocortin (POMC)-derived peptides, i.e., α-melanocyte-stimulating hormone (α-MSH), adrenocorticotropin (ACTH) and β-endorphin (β-ED), and sympathetic neuropeptides like ...

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Item type:Article
Date:26 January 2018
Institutions:Medicine > Lehrstuhl für Orthopädie
Projects:Open Access Publizieren (DFG)
Identification Number:
ValueType
10.3390/ijms19020367DOI
Keywords:proopiomelanocortin; alpha-MSH; VIP; NPY; osteoarthritis; neuroendocrine; PACAP
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:36858
Owner only: item control page

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