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Impedance-based analysis of 3D tissue models: A novel measurement setup for novel measurement modes

URN to cite this document:
urn:nbn:de:bvb:355-epub-354425
DOI to cite this document:
10.5283/epub.36956
Hupf, Christina
Date of publication of this fulltext: 06 Apr 2018 06:35


Abstract (English)

The use of 3D tissue models is an emerging branch of cell-based in vitro assays. However, the advancement of appropriate readout techniques capable of reaching into the center of those cell aggregates proceeds rather slowly. This thesis addresses the characterization and testing of a new impedance-based device to analyze 3D multicellular spheroids non-invasively and label-free. The new device ...

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Translation of the abstract (German)

In Zell-basierten Analyseverfahren werden 2D planare Zellmodelle zunehmend durch 3D Gewebemodelle ersetzt. Die Weiterentwicklung und Anpassung der Auslesemethoden, um das neue Modellsystem bis zu seinem Kern zu analysieren ist jedoch ein langwieriger Prozess. In dieser Arbeit wird ein neu entwickeltes Impedanz-basiertes Messsystem zur nichtinvasiven und markierungsfreien Analyse von 3D ...

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