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Protective effect of xanthohumol on toxin-induced liver inflammation and fibrosis

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Dorn, Christoph ; Heilmann, Jörg ; Hellerbrand, Claus
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Date of publication of this fulltext: 11 Apr 2018 10:17


Xanthohumol, the major prenylated chalcone found in hops, is known for its anti-inflammatory properties. We have recently shown that xanthohumol inhibits hepatic inflammation and fibrosis in a murine model of nonalcoholic steatohepatitis. The aim of this study was to investigate the effect of xanthohumol in an acute model of liver injury. Carbon tetrachloride (CCl(4)), an industrial solvent, is a ...


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