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Xanthohumol feeding does not impair organ function and homoeostasis in mice

Dorn, Christoph ; Bataille, Frauke ; Gaebele, Erwin ; Heilmann, Jörg ; Hellerbrand, Claus

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Abstract

Xanthohumol, the major prenylated chalcone found in hops, is known to exert several beneficial effects but only few studies evaluated the safety profile of this natural compound with in part discrepant results. Here, we fed female BALB/c mice with a standard diet supplemented with xanthohumol for 3 weeks, and thus, achieved a daily dose of approximately 1000 mg xanthohumol/kg body weight. There ...

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