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Sterol Regulatory Element-Binding Protein 2 (SREBP2) Activation after Excess Triglyceride Storage Induces Chemerin in Hypertrophic Adipocytes

Bauer, Sabrina, Wanninger, Josef, Schmidhofer, Sandra, Weigert, Johanna, Neumeier, Markus, Dorn, Christoph , Hellerbrand, Claus, Zimara, Nicole, Schäffler, Andreas, Aslanidis, Charalampos and Buechler, Christa (2011) Sterol Regulatory Element-Binding Protein 2 (SREBP2) Activation after Excess Triglyceride Storage Induces Chemerin in Hypertrophic Adipocytes. Endocrinology 152 (1), pp. 26-35.

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Other URL: http://doi.org/10.1210/en.2010-1157


Abstract

Chemerin is an adipokine whose systemic concentration and adipose tissue expression is increased in obesity. Chemerin is highly abundant in adipocytes, yet the molecular mechanisms mediating its further induction in obesity have not been clarified. Adipocyte hypertrophy contributes to dysregulated adipokine synthesis, and we hypothesized that excess loading with free fatty acids (FFA) stimulates ...

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Item type:Article
Date:2011
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Group Clinical Pharmacy (Dr. Dorn)
Identification Number:
ValueType
10.1210/en.2010-1157DOI
Dewey Decimal Classification:600 Technology > 615 Pharmacy
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:37041

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  • Sterol Regulatory Element-Binding Protein 2 (SREBP2) Activation after Excess Triglyceride Storage Induces Chemerin in Hypertrophic Adipocytes. (Deposited on 12 Apr 2018 09:57) [Currently displayed]
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