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- URN to cite this document:
- urn:nbn:de:bvb:355-epub-370477
- DOI to cite this document:
- 10.5283/epub.37047
Alternative links to fulltext:Publisher
Abstract
Nonalcoholic fatty liver disease (NAFLD) is characterized by hepatic lipid accumulation which starts with simple hepatic steatosis and may progress toward inflammation (nonalcoholic steatohepatitis [NASH]). Fatty acid synthase (FASN) catalyzes the last step in fatty acid biosynthesis, and thus, it is believed to be a major determinant of the maximal hepatic capacity to generate fatty acids by de ...

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