Mayr, Judith, Grijalvo, Santiago 
, Bachl, Jürgen, Eritja, Ramon , Díaz Díaz, David and make_name_string expected hash reference
(2017)
Transfection of Antisense Oligonucleotides Mediated by Cationic Vesicles Based on Non-Ionic Surfactant and Polycations Bearing Quaternary Ammonium Moieties.
International Journal of Molecular Sciences 18, p. 1169.
| License: Allianz- bzw. Nationallizenz PDF - Published Version Download (1MB) |
Dieser Artikel ist in einer Zeitschrift aus dem Directory of Open Access (DOAJ) publiziert.
Abstract
Three different ionene polymers with varying quaternary ammonium moieties were used as a proof of concept for the formulation of antisense oligonucleotides, which are capable of inhibiting Renilla luciferase messenger ribonucleic acid (mRNA). Cationic vesicles, consisting of cationic polymer, antisense oligonucleotide (Luc) and non-ionic surfactant polysorbate 80, were investigated regarding ...
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| Item type: | Article | ||||
|---|---|---|---|---|---|
| Date: | 2017 | ||||
| Institutions: | Chemistry and Pharmacy > Institut für Organische Chemie > Arbeitskreis Prof. Dr. David Díaz Díaz | ||||
| Identification Number: |
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| Keywords: | GENE DELIVERY; DNA; POLYMERS; TOXICITY; AMPHIPHILE; EFFICIENCY; HYDRATION; IONENES; COMPLEX; AGENTS; antisense oligonucleotide; cationic polymers; cationic vesicles; ionenes; transfection; polycations; polyplexes; quaternary ammonium | ||||
| Dewey Decimal Classification: | 500 Science > 570 Life sciences | ||||
| Status: | Published | ||||
| Refereed: | Yes, this version has been refereed | ||||
| Created at the University of Regensburg: | Yes | ||||
| Item ID: | 37456 |
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