Proteome Analysis of Human Follicular Thyroid Cancer Cells Exposed to the Random Positioning Machine

URN to cite this document:: urn:nbn:de:bvb:355-epub-374654
DOI to cite this document:: 10.5283/epub.37465

Bauer, Johann ; Kopp, Sascha ; Schlagberger, Elisabeth Maria ; Grosse, Jirka

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Date of publication of this fulltext: 05 Jul 2018 12:16

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Abstract

Several years ago, we detected the formation of multicellular spheroids in experiments with human thyroid cancer cells cultured on the Random Positioning Machine (RPM), a ground-based model to simulate microgravity by continuously changing the orientation of samples. Since then, we have studied cellular mechanisms triggering the cells to leave a monolayer and aggregate to spheroids. Our work ...