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Proteome Analysis of Human Follicular Thyroid Cancer Cells Exposed to the Random Positioning Machine

Bauer, Johann, Kopp, Sascha, Schlagberger, Elisabeth Maria, Grosse, Jirka, make_name_string expected hash reference , make_name_string expected hash reference, make_name_string expected hash reference, make_name_string expected hash reference, make_name_string expected hash reference and make_name_string expected hash reference (2017) Proteome Analysis of Human Follicular Thyroid Cancer Cells Exposed to the Random Positioning Machine. International Journal of Molecular Sciences 18, p. 564.

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Date of publication of this fulltext: 05 Jul 2018 12:16

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Abstract

Several years ago, we detected the formation of multicellular spheroids in experiments with human thyroid cancer cells cultured on the Random Positioning Machine (RPM), a ground-based model to simulate microgravity by continuously changing the orientation of samples. Since then, we have studied cellular mechanisms triggering the cells to leave a monolayer and aggregate to spheroids. Our work ...

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Item type:Article
Date:2017
Institutions:Medicine > Abteilung für Nuklearmedizin
Identification Number:
ValueType
10.3390/ijms18030546DOI
Keywords:FOCAL ADHESION KINASE; SIMULATED MICROGRAVITY CONDITIONS; GTPASE-ACTIVATING PROTEIN; SPHEROID FORMATION; 3-DIMENSIONAL GROWTH; CARCINOMA CELLS; IDENTIFICATION; MIGRATION; PAXILLIN; ASAP1; cellular compartments; mass spectrometry; proteomics; pathway analysis; random positioning machine
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:37465
Owner only: item control page

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