Low hepatitis E virus RNA prevalence in a large-scale survey of United States source plasma donors

URN to cite this document:: urn:nbn:de:bvb:355-epub-374997
DOI to cite this document:: 10.5283/epub.37499

Roth, Nathan J. ; Schäfer, Wolfram ; Alexander, Rick ; Elliott, Kevin ; Elliott-Browne, Wlenyeno ; Knowles, Jonathan ; Wenzel, Jürgen J.

; Simon, Toby L.

License: Creative Commons: Attribution-Noncommercial 3.0
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Date of publication of this fulltext: 19 Jul 2018 09:36

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Abstract

BACKGROUND: Hepatitis E virus (HEV) is a small, nonenveloped, single-stranded, RNA virus of emerging concern in industrialized countries. HEV transmission through transfusion of blood components has been reported, but not via plasma-derived medicinal products (PDMPs) manufactured with virus inactivation and/or removal steps. This study aimed to determine the prevalence of HEV among US source ...