Regulation and Function of TMEM16F in Renal Podocytes

URN to cite this document:: urn:nbn:de:bvb:355-epub-376186
DOI to cite this document:: 10.5283/epub.37618

Schenk, Laura K. ; Ousingsawat, Jiraporn ; Skryabin, Boris V.

; Schreiber, Rainer ; Pavenstädt, Hermann ; Kunzelmann, Karl

License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 29 Aug 2018 13:01

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Abstract

The Ca2+-activated phospholipid scramblase and ion channel TMEM16F is expressed in podocytes of renal glomeruli. Podocytes are specialized cells that form interdigitating foot processes as an essential component of the glomerular filter. These cells, which participate in generation of the primary urine, are often affected during primary glomerular diseases, such as glomerulonephritis and ...