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Safety, Tolerability and Clinical Effects of a Rapid Dose Titration of Subcutaneous Treprostinil Therapy in Pulmonary Arterial Hypertension: A Prospective Multi-Centre Trial

Grüning, Ekkehard, Benjamin, Nicola, Lange, Tobias J., Krueger, Ulrich, Klose, Hans, Neuroher, Claus, Wilkens, Heinrike, Halank, Michael, Seyfarth, Hans-Jürgen, Held, Matthias, Traube, Andrew, Pernow, Michelle, Grover, E. Robert, Egenlauf, Benjamin, Gerhardt, Felix, Viethen, Thomas and Rosenkranz, Stephan (2016) Safety, Tolerability and Clinical Effects of a Rapid Dose Titration of Subcutaneous Treprostinil Therapy in Pulmonary Arterial Hypertension: A Prospective Multi-Centre Trial. Respiration 92 (6), pp. 362-370.

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Date of publication of this fulltext: 28 Aug 2018 14:38

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Abstract

Background: Subcutaneous treprostinil has dose-dependent beneficial effects in patients with severe pulmonary arterial hypertension, but adverse effects like infusion site pain can lead to treatment discontinuation. Objectives: The objective of this study was to evaluate safety, tolerability and clinical effects of a rapid up-titration dosing regimen of subcutaneous treprostinil using proactive ...

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Item type:Article
Date:2016
Institutions:Medicine > Lehrstuhl für Innere Medizin II
Identification Number:
ValueType
10.1159/000450759DOI
Keywords:Pulmonary arterial hypertension, Subcutaneous infusion, Treprostinil
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:37639
Owner only: item control page

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