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Frequency of TERT Promoter Mutations in Prostate Cancer

Stoehr, Robert, Taubert, Helge, Zinnall, Ulrike, Giedl, Johannes, Gaisa, Nadine T., Burger, Maximilian, Ruemmele, Petra, Hurst, Carolyn D., Knowles, Margaret A., Wullich, Bernd and Hartmann, Arndt (2015) Frequency of TERT Promoter Mutations in Prostate Cancer. Pathobiology 82 (2), pp. 53-57.

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Date of publication of this fulltext: 28 Aug 2018 14:03

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Other URL: https://www.karger.com/Article/FullText/381903


Objective: Recently, recurrent mutations within the core promoter of the human telomerase reverse transcriptase (TERT) gene generating consensus binding sites for ETS transcription factor family members were described in melanomas and other malignancies (e.g. bladder cancer, hepatocellular carcinoma). These mutations were discussed as early drivers for malignant transformation. In prostate cancer ...


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Item type:Article
Institutions:Medicine > Lehrstuhl für Pathologie
Identification Number:
Keywords:TERT, Promoter, Mutation, SNaPshot analysis, Sanger sequencing, Prostate cancer
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:37659
Owner only: item control page


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