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Functional characterization of SPRR5 in neoplasia and epidermal homeostasis

Ziegler, Christian (2019) Functional characterization of SPRR5 in neoplasia and epidermal homeostasis. PhD, Universität Regensburg.

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Date of publication of this fulltext: 09 Oct 2019 10:36

Abstract (English)

Constituting an effective barrier against environmental challenges such as pathogen invasion, UV-radiation or prevention of extensive water loss, the epidermis as the outermost layer of the human skin has to be constantly regenerated in order to maintain its protective function. During this highly elaborate and delicate process of epidermal rejuvenation, progenitor keratinocytes conduct a ...

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Translation of the abstract (German)

Als effektive Barriere gegen Umwelteinflüsse wie UV-Strahlung, Vermeidung eines starken Wasserverlustes oder Pathogeninvasion muss die Epidermis als äußerste Schicht der menschlichen Haut konstant regeneriert werden, um ihre schützende Funktion aufrecht erhalten zu können. Im Laufe dieses hochkomplexen und minutiös gesteuerten Prozesses der epidermalen Verjüngung durchlaufen Vorläufer ...

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Item type:Thesis of the University of Regensburg (PhD)
Date:9 October 2019
Referee:PD Dr. Markus Kretz
Date of exam:8 October 2018
Institutions:Biology, Preclinical Medicine > Institut für Biochemie, Genetik und Mikrobiologie > Lehrstuhl für Biochemie I
Keywords:Skin, lncRNA, non-coding RNA, Epidermis
Dewey Decimal Classification:500 Science > 570 Life sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:37836
Owner only: item control page

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