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Delivery of Cytomegalovirus T cell antigens for diagnostic and vaccination purposes

Kiener, Richard (2019) Delivery of Cytomegalovirus T cell antigens for diagnostic and vaccination purposes. PhD, Universität Regensburg.

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Date of publication of this fulltext: 01 Apr 2019 05:32

Abstract (English)

Human Cytomegalovirus (CMV) is a highly prevalent β-herpesvirus that establishes life-long latency after primary infection. Congenital CMV infection is the most common viral compli-cation in newborns, causing a number of late sequelae that range from impaired hearing to mental retardation. At the same time, managing CMV reactivation during immunosup-pression remains a major hurdle in ...

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Translation of the abstract (German)

Das humane Zytomegalievirus (CMV) weist weltweit hohe Seroprävalenz auf und etabliert nach der Primärinfektion lebenslange Latenz. Infektionen mit CMV sind die häufigste virale Komplikation bei Neugeborenen und verursachen eine Reihe von Spätfolgen wie Schwer-hörigkeit oder geistige Behinderungen. Zusätzlich stellen CMV Reaktivierungen die bedeu-tendste pathogen-assoziierte Komplikation bei ...

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Item type:Thesis of the University of Regensburg (PhD)
Date:1 April 2019
Referee:Prof. Dr. Ralf Wagner
Date of exam:15 October 2018
Institutions:Medicine > Lehrstuhl für Medizinische Mikrobiologie und Hygiene
Keywords:CMV, T cells, viral vectors, immune monitoring
Dewey Decimal Classification:500 Science > 500 Natural sciences & mathematics
500 Science > 570 Life sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:37860
Owner only: item control page

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