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Drug Repurposing of Metabolic Agents in Malignant Glioma

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Seliger, Corinna ; Hau, Peter
Date of publication of this fulltext: 22 Nov 2018 08:42


Gliomas are highly invasive brain tumors with short patient survival. One major pathogenic factor is aberrant tumor metabolism, which may be targeted with different specific and unspecific agents. Drug repurposing is of increasing interest in glioma research. Drugs interfering with the patient’s metabolism may also influence glioma metabolism. In this review, we outline definitions and methods ...


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