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The Importance of Physioxia in Mesenchymal Stem Cell Chondrogenesis and the Mechanisms Controlling Its Response

URN to cite this document:
urn:nbn:de:bvb:355-epub-382687
DOI to cite this document:
10.5283/epub.38268
Pattappa, Girish ; Johnstone, Brian ; Zellner, Johannes ; Docheva, Denitsa ; Angele, Peter
Date of publication of this fulltext: 31 Jan 2019 09:56



Abstract

Articular cartilage covers the surface of synovial joints and enables joint movement. However, it is susceptible to progressive degeneration with age that can be accelerated by either previous joint injury or meniscectomy. This degenerative disease is known as osteoarthritis (OA) and it greatly affects the adult population. Cell-based tissue engineering provides a possible solution for treating ...

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