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The Importance of Physioxia in Mesenchymal Stem Cell Chondrogenesis and the Mechanisms Controlling Its Response

Pattappa, Girish , Johnstone, Brian, Zellner, Johannes, Docheva, Denitsa and Angele, Peter (2019) The Importance of Physioxia in Mesenchymal Stem Cell Chondrogenesis and the Mechanisms Controlling Its Response. International Journal of Molecular Sciences 20 (3), p. 484.

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Date of publication of this fulltext: 31 Jan 2019 09:56

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Other URL: http://doi.org/10.3390/ijms20030484, https://www.mdpi.com/1422-0067/20/3/484


Abstract

Articular cartilage covers the surface of synovial joints and enables joint movement. However, it is susceptible to progressive degeneration with age that can be accelerated by either previous joint injury or meniscectomy. This degenerative disease is known as osteoarthritis (OA) and it greatly affects the adult population. Cell-based tissue engineering provides a possible solution for treating ...

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Item type:Article
Date:23 January 2019
Institutions:Medicine > Lehrstuhl für Unfallchirurgie
Projects:Open Access Publizieren (DFG)
Identification Number:
ValueType
10.3390/ijms20030484DOI
Keywords:mesenchymal stem cells; chondrogenesis; hypoxia; cartilage; hypertrophy; hypoxia inducible factors; early osteoarthritis
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:38268
Owner only: item control page

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