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Interaction of funtionalized nanoparticles with serum proteins and its impact on colloidal stability and cargo leaching

Abstiens, Kathrin ; Maslanka Figeruoa, Sara ; Gregoritza, Manuel ; Göpferich, Achim


The majority of effort in the area of polymeric nanocarriers is aimed at providing controlled drug delivery in vivo. Therefore, it is essential to understand the delicate interplay of polymeric NPs with serum proteins in order to forecast their performance in a biological system. In this study, the interaction of serum proteins with functionalized polymeric colloids as a function of particle ...


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