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The adipo‐fibrokine activin A is associated with metabolic abnormalities and left ventricular diastolic dysfunction in obese patients

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Zeller, Judith ; Krüger, Carolin ; Lamounier‐Zepter, Valeria ; Sag, Sabine ; Strack, Christina ; Mohr, Margareta ; Loew, Thomas ; Schmitz, Gerd ; Maier, Lars ; Fischer, Marcus ; Baessler, Andrea
Date of publication of this fulltext: 12 Feb 2019 12:37


Aims Left ventricular diastolic dysfunction (LVDD) is common in obese subjects, and a relationship between epicardial adipose tissue (EAT), increased adipocytokines, and cardiovascular diseases has been reported. This study sought to examine as to whether the adipo-fibrokine activin A is a link between increased EAT, the metabolic syndrome (MetS), and LVDD in severely obese subjects. Methods and ...


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