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Gold-Tagged Polymeric Nanoparticles with Spatially Controlled Composition for Enhanced Detectability in Biological Environments

Abstiens, Kathrin , Fleischmann, Daniel, Gregoritza, Manuel and Göpferich, Achim (2019) Gold-Tagged Polymeric Nanoparticles with Spatially Controlled Composition for Enhanced Detectability in Biological Environments. ACS Applied Nano Materials 2 (2), pp. 917-926.

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Other URL: https://pubs.acs.org/doi/10.1021/acsanm.8b02165


Abstract

Organic nanoparticles offer the advantage of high biocompatibility for biomedical applications but suffer frequently from poor visibility in biological environments. While fluorescent-labeling is convenient and allows for fast and extensive histological analysis, fluorescence imaging and quantitative analysis are limited by low resolution and significantly hindered by tissue autofluorescence. ...

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Item type:Article
Date:2019
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical Technology (Prof. Göpferich)
Identification Number:
ValueType
10.1021/acsanm.8b02165DOI
Keywords:contrast agent; gold; hybrid; PLGA; polymeric nanoparticles; TEM
Dewey Decimal Classification:600 Technology > 615 Pharmacy
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:38327
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