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Adrenal gland plasticity in lactating rats and mice is sufficient to maintain basal hypersecretion of corticosterone

Perani, Clara V. ; Langgartner, Dominik ; Uschold-Schmidt, Nicole ; Füchsl, Andrea M. ; Neumann, Inga D. ; Reber, Stefan O. ; Slattery, David A.



Abstract

Increased basal glucocorticoid secretion and a reduced glucocorticoid response during acute stress, despite only minor changes in the secretion of the major secretagogue adrenocorticotropic hormone (ACTH), have been documented in the peripartum period in several species. We recently showed that the adrenal gland, the site of glucocorticoid synthesis, undergoes substantial postpartum-associated ...

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