Go to content
UR Home

Hepatocyte-specific Smad7 deletion accelerates DEN-induced HCC via activation of STAT3 signaling in mice

Feng, T, Dzieran, J, Yuan, X, Dropmann, A, Maass, T, Teufel, A, Marhenke, S, Gaiser, T, Rückert, F, Kleiter, I, Kanzler, S, Ebert, M P, Vogel, A, ten Dijke, P, Dooley, S and Meindl-Beinker, N M (2017) Hepatocyte-specific Smad7 deletion accelerates DEN-induced HCC via activation of STAT3 signaling in mice. Oncogenesis 6 (1), e294-e294.

Full text not available from this repository.

at publisher (via DOI)

Other URL: http://doi.org/10.1038/oncsis.2016.85

Dieser Artikel ist in einer Zeitschrift aus dem Directory of Open Access (DOAJ) publiziert.


Abstract

TGF-beta signaling in liver cells has variant roles in the dynamics of liver diseases, including hepatocellular carcinoma (HCC). We previously found a correlation of high levels of the important endogenous negative TGF-beta signaling regulator SMAD7 with better clinical outcome in HCC patients. However, the underlying tumor-suppressive molecular mechanisms are still unclear. Here, we show that ...

plus


Export bibliographical data



Item type:Article
Date:2017
Institutions:Medicine > Lehrstuhl für Innere Medizin I
Identification Number:
ValueType
10.1038/oncsis.2016.85DOI
Keywords:HUMAN HEPATOCELLULAR-CARCINOMA; TGF-BETA; OXIDATIVE STRESS; LIVER-CANCER; MOUSE-LIVER; COMPENSATORY PROLIFERATION; IN-VITRO; KAPPA-B; CELLS; HEPATOCARCINOGENESIS;
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:38497
Owner only: item control page
  1. Homepage UR

University Library

Publication Server

Contact:

Publishing: oa@ur.de

Dissertations: dissertationen@ur.de

Research data: daten@ur.de

Contact persons