Feng, T, Dzieran, J, Yuan, X, Dropmann, A, Maass, T, Teufel, A, Marhenke, S, Gaiser, T, Rückert, F, Kleiter, I, Kanzler, S, Ebert, M P, Vogel, A, ten Dijke, P, Dooley, S and Meindl-Beinker, N M (2017) Hepatocyte-specific Smad7 deletion accelerates DEN-induced HCC via activation of STAT3 signaling in mice. Oncogenesis 6 (1), e294-e294.
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Other URL: http://doi.org/10.1038/oncsis.2016.85
Dieser Artikel ist in einer Zeitschrift aus dem Directory of Open Access (DOAJ) publiziert.
Abstract
TGF-beta signaling in liver cells has variant roles in the dynamics of liver diseases, including hepatocellular carcinoma (HCC). We previously found a correlation of high levels of the important endogenous negative TGF-beta signaling regulator SMAD7 with better clinical outcome in HCC patients. However, the underlying tumor-suppressive molecular mechanisms are still unclear. Here, we show that ...
Export bibliographical data
| Item type: | Article | ||||
|---|---|---|---|---|---|
| Date: | 2017 | ||||
| Institutions: | Medicine > Lehrstuhl für Innere Medizin I | ||||
| Identification Number: |
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| Keywords: | HUMAN HEPATOCELLULAR-CARCINOMA; TGF-BETA; OXIDATIVE STRESS; LIVER-CANCER; MOUSE-LIVER; COMPENSATORY PROLIFERATION; IN-VITRO; KAPPA-B; CELLS; HEPATOCARCINOGENESIS; | ||||
| Dewey Decimal Classification: | 600 Technology > 610 Medical sciences Medicine | ||||
| Status: | Published | ||||
| Refereed: | Yes, this version has been refereed | ||||
| Created at the University of Regensburg: | Yes | ||||
| Item ID: | 38497 |
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