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Synthesis and Regioselectivity in the Alkylation of 1,3,4-Oxadiazolethiones with Dihaloalkanes and Epichlorohydrin

El Ashry, El Sayed H. ; Boraei, Ahmed T. A. ; Duerkop, Axel


[GRAPHICS] The regioselectivity in the alkylation of 1,3,4-oxadiazolethiones with dihaloalkanes was found that it depends mainly on the length of the alkyl chain connecting the two halides; moreover, the formation of thiirane ring instead of epoxide ring during the alkylation with epichlorohydrin was surprising.

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