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Childhood adversity impacts on brain subcortical structures relevant to depression

Frodl, Thomas, Janowitz, Deborah, Schmaal, Lianne, Tozzi, Leonardo , Dobrowolny, Henrik, Stein, Dan J. , Veltman, Dick J., Wittfeld, Katharina, van Erp, Theo G.M., Jahanshad, Neda, Block, Andrea, Hegenscheid, Katrin, Völzke, Henry, Lagopoulos, Jim, Hatton, Sean N. , Hickie, Ian B., Frey, Eva Maria, Carballedo, Angela, Brooks, Samantha J. , Vuletic, Daniella, Uhlmann, Anne, Veer, Ilya M., Walter, Henrik, Schnell, Knut, Grotegerd, Dominik, Arolt, Volker, Kugel, Harald, Schramm, Elisabeth, Konrad, Carsten, Zurowski, Bartosz, Baune, Bernhard T., van der Wee, Nic J.A., van Tol, Marie-Jose, Penninx, Brenda W.J.H., Thompson, Paul M. , Hibar, Derrek P., Dannlowski, Udo and Grabe, Hans J. (2017) Childhood adversity impacts on brain subcortical structures relevant to depression. Journal of Psychiatric Research 86, pp. 58-65.

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Other URL: http://doi.org/10.1016/j.jpsychires.2016.11.010


Abstract

Childhood adversity plays an important role for development of major depressive disorder (MDD). There are differences in subcortical brain structures between patients with MDD and healthy controls, but the specific impact of childhood adversity on such structures in MDD remains unclear. Thus, aim of the present study was to investigate whether childhood adversity is associated with subcortical ...

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Item type:Article
Date:2017
Institutions:Medicine > Lehrstuhl für Psychiatrie und Psychotherapie
Identification Number:
ValueType
10.1016/j.jpsychires.2016.11.010DOI
Keywords:POSTTRAUMATIC-STRESS-DISORDER; MEDIAL PREFRONTAL CORTEX; CA3 PYRAMIDAL NEURONS; HIPPOCAMPAL VOLUME; MAJOR DEPRESSION; MALTREATMENT; METAANALYSIS; MORPHOLOGY; SEVERITY; AMYGDALA; Depression; Childhood adversity; MRI; Caudate; Hippocampus; ENIGMA
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:38670
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