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Defibrotide for children and adults with hepatic veno-occlusive disease post hematopoietic cell transplantation

Corbacioglu, Selim ; Richardson, Paul G.



Abstract

Introduction: Hepatic veno-occlusive disease/sinusoidal obstruction syndrome (VOD/SOS) is a complication that is typically associated with conditioning for hematopoietic stem cell transplantation (HSCT). In patients with concomitant multi-organ dysfunction, mortality may be >80%. Recently, the European Society for Blood and Marrow Transplantation established separate criteria for diagnosis and ...

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