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The Use of Neoadjuvant Chemotherapy in Patients With Urothelial Carcinoma of the Bladder: Current Practice Among Clinicians

Martini, Thomas ; Gilfrich, Christian ; Mayr, Roman ; Burger, Maximilian ; Pycha, Armin ; Aziz, Atiqullah ; Gierth, Michael ; Stief, Christian G. ; Müller, Stefan C. ; Wagenlehner, Florian ; Roigas, Jan ; Hakenberg, Oliver W. ; Roghmann, Florian ; Nuhn, Philipp ; Wirth, Manfred ; Novotny, Vladimir ; Hadaschik, Boris ; Grimm, Marc-Oliver ; Schramek, Paul ; Haferkamp, Axel ; Colleselli, Daniela ; Kloss, Birgit ; Herrmann, Edwin ; Fisch, Margit ; May, Matthias ; Bolenz, Christian


Neoadjuvant chemotherapy before radical cystectomy is recommended in patients with bladder cancer in clinical stages T2-T4a, cN0M0. We analyzed the frequency and current practice of neoadjuvant chemotherapy in 679 patients using uni- and multivariable regression analyses and using a questionnaire. We found a great discrepancy between guideline recommendations and practice patterns, despite ...


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