Akey, Joshua M. ; Shungin, Dmitry ; Deng, Wei Q. 
; Varga, Tibor V. ; Luan, Jian'an ; Mihailov, Evelin ; Metspalu, Andres ; Morris, Andrew P. ; Forouhi, Nita G. ; Lindgren, Cecilia ; Magnusson, Patrik K. E. ; Pedersen, Nancy L. ; Hallmans, Göran ; Chu, Audrey Y. ; Justice, Anne E. ; Graff, Mariaelisa ; Winkler, Thomas W. ; Rose, Lynda M. ; Langenberg, Claudia ; Cupples, L. Adrienne ; Ridker, Paul M. ; Wareham, Nicholas J. ; Ong, Ken K. ; Loos, Ruth J. F. ; Chasman, Daniel I. ; Ingelsson, Erik ; Kilpeläinen, Tuomas O. ; Scott, Robert A. ; Mägi, Reedik ; Pare, Guillaume ; Franks, Paul W.
; Varga, Tibor V. ; Luan, Jian'an ; Mihailov, Evelin ; Metspalu, Andres ; Morris, Andrew P. ; Forouhi, Nita G. ; Lindgren, Cecilia ; Magnusson, Patrik K. E. ; Pedersen, Nancy L. ; Hallmans, Göran ; Chu, Audrey Y. ; Justice, Anne E. ; Graff, Mariaelisa ; Winkler, Thomas W. ; Rose, Lynda M. ; Langenberg, Claudia ; Cupples, L. Adrienne ; Ridker, Paul M. ; Wareham, Nicholas J. ; Ong, Ken K. ; Loos, Ruth J. F. ; Chasman, Daniel I. ; Ingelsson, Erik ; Kilpeläinen, Tuomas O. ; Scott, Robert A. ; Mägi, Reedik ; Pare, Guillaume ; Franks, Paul W. 
Zusammenfassung
Phenotypic variance heterogeneity across genotypes at a single nucleotide polymorphism (SNP) may reflect underlying gene-environment (GxE) or gene-gene interactions. We modeled variance heterogeneity for blood lipids and BMI in up to 44,211 participants and investigated relationships between variance effects (P-v), GxE interaction effects (with smoking and physical activity), and marginal genetic ...
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