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Early postoperative tumor progression predicts clinical outcome in glioblastoma—implication for clinical trials

Merkel, Andreas, Soeldner, Dorothea, Wendl, Christina, Urkan, Dilek, Kuramatsu, Joji B., Seliger, Corinna, Proescholdt, Martin, Eyupoglu, Ilker Y., Hau, Peter and Uhl, Martin (2017) Early postoperative tumor progression predicts clinical outcome in glioblastoma—implication for clinical trials. Journal of Neuro-Oncology 132 (2), pp. 249-254.

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Other URL: http://doi.org/10.1007/s11060-016-2362-z


Abstract

Molecular markers define the diagnosis of glioblastoma in the new WHO classification of 2016, challenging neuro-oncology centers to provide timely treatment initiation. The aim of this study was to determine whether a time delay to treatment initiation was accompanied by signs of early tumor progression in an MRI before the start of radiotherapy, and, if so, whether this influences the survival ...

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Item type:Article
Date:2017
Institutions:Medicine > Lehrstuhl für Unfallchirurgie
Medicine > Lehrstuhl für Neurologie
Identification Number:
ValueType
10.1007/s11060-016-2362-zDOI
Keywords:NEWLY-DIAGNOSED GLIOBLASTOMA; RADIOTHERAPY; MULTIFORME; SURVIVAL; CHEMORADIATION; GROWTH; IMPACT; DELAY; Glioblastoma; MGMT promoter; Treatment delay; Magnetic resonance imaging; Survival
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:39126
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