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A Randomised, Double-blind, Placebo-controlled Trial ofTrichuris suisova in Active Crohn’s disease

Schölmerich, Jürgen, Fellermann, Klaus, Seibold, Frank W., Rogler, Gerhard, Langhorst, Jost, Howaldt, Stefanie, Novacek, Gottfried, Petersen, Andreas Munk , Bachmann, Oliver , Matthes, Harald, Hesselbarth, Norbert, Teich, Niels, Wehkamp, Jan, Klaus, Jochen, Ott, Claudia, Dilger, Karin, Greinwald, Roland and Mueller, Ralph (2016) A Randomised, Double-blind, Placebo-controlled Trial ofTrichuris suisova in Active Crohn’s disease. Journal of Crohn's and Colitis, jjw184.

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Other URL: http://doi.org/10.1093/ecco-jcc/jjw184


Abstract

Background and Aims: To investigate the efficacy and safety of three different dosages of embryonated, viable eggs of Trichuris suis [TSO] versus placebo for induction of remission in mildly-to-moderately active ileocolonic, uncomplicated Crohn's disease [CD]. Methods: Adults with active CD [n = 252] randomly received six fortnightly doses of 250, 2500, or 7500 TSO/15 ml suspension/day [TSO 250, ...

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Item type:Article
Date:2016
Institutions:Medicine > Lehrstuhl für Innere Medizin I
Identification Number:
ValueType
10.1093/ecco-jcc/jjw184DOI
Keywords:INFLAMMATORY BOWEL DISEASES; HELIGMOSOMOIDES-POLYGYRUS; ULCERATIVE-COLITIS; ACTIVITY INDEX; IMMUNE-SYSTEM; INFECTION; AUTOIMMUNE; THERAPY; HYGIENE; PARASITES; Crohn's disease; randomized; Trichuris suis ova [TSO]
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:39145
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