; Grimm, Jennifer ; Hennighausen, Lars ; Kugler, Claudia ; Reese, Imke ; Ring, Johannes ; Schäkel, Knut ; Schmitt, Jochen ; Seikowski, Kurt ; von Stebut, Esther ; Wagner, Nicola ; Waßmann-Otto, Anja ; Wienke-Graul, Ute ; Weisshaar, Elke ; Worm, Margitta ; Gieler, Uwe ; Kupfer, Joerg ; Brauner, Katrin ; Dölle, Sabine ; Ehmann, Laura ; Hagmaier, Ute ; Eberlein, Susanne ; Kroth, Julia ; Lämmerhirt, Katja ; Landleiter, Rosemarie ; Lorenz, Ute ; Lüdemann, Anja ; Matterne, Uwe ; Mitzel-Rink, Heidrun ; Niebuhr, Margarete ; Rehberg, Tessa ; Vogel, Sandra ; Wichmann, Katja | Dokumentenart: | Artikel | ||||
|---|---|---|---|---|---|
| Titel eines Journals oder einer Zeitschrift: | Journal of Allergy and Clinical Immunology | ||||
| Verlag: | MOSBY-ELSEVIER | ||||
| Ort der Veröffentlichung: | NEW YORK | ||||
| Band: | 140 | ||||
| Nummer des Zeitschriftenheftes oder des Kapitels: | 3 | ||||
| Seitenbereich: | 845-853.e3 | ||||
| Datum: | 2017 | ||||
| Institutionen: | Medizin > Institut für Epidemiologie und Präventivmedizin > Medizinische Soziologie | ||||
| Identifikationsnummer: |
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| Stichwörter / Keywords: | QUALITY-OF-LIFE; NATIONAL-HEALTH CARE; PATIENTS PERSPECTIVE; PEDIATRIC-PATIENTS; CLINICAL SIGNS; POSITION PAPER; DISEASE BURDEN; ECZEMA; DERMATOLOGY; VALIDATION; Atopic dermatitis; adulthood; patient education; multi-professional; psychosocial; disease severity; quality of life; coping | ||||
| Dewey-Dezimal-Klassifikation: | 600 Technik, Medizin, angewandte Wissenschaften > 610 Medizin | ||||
| Status: | Veröffentlicht | ||||
| Begutachtet: | Ja, diese Version wurde begutachtet | ||||
| An der Universität Regensburg entstanden: | Ja | ||||
| Dokumenten-ID: | 39214 |
Zusammenfassung
Background: Atopic dermatitis (AD) is a chronic relapsing skin disease prevalent in 1% to 3% of adults in Western industrialized countries. Objective: We sought to investigate the effectiveness of educational training in an outpatient setting on coping with the disease, quality of life, symptoms, and severity in adults with AD. Methods: In this German prospective, randomized controlled ...

Zusammenfassung
Background: Atopic dermatitis (AD) is a chronic relapsing skin disease prevalent in 1% to 3% of adults in Western industrialized countries. Objective: We sought to investigate the effectiveness of educational training in an outpatient setting on coping with the disease, quality of life, symptoms, and severity in adults with AD. Methods: In this German prospective, randomized controlled multicenter study, adult patients with moderate-to-severe AD were educated by referring to a comprehensive 12-hour training manual consented by a multiprofessional study group from different centers (Arbeitsgemeinschaft Neurodermitisschulung fur Erwachsene [ARNE]). Patients were randomly allocated to the intervention or waiting control groups. Study visits were performed at baseline and after 1 year (1 year of follow-up). Primary outcomes were defined as a decrease in (1) "catastrophizing cognitions'' with respect to itching (Juckreiz-Kognitions-Fragebogen questionnaire), (2) "social anxiety'' (Marburger Hautfragebogen questionnaire), (3) subjective burden by symptoms of the disease (Skindex-29 questionnaire), and (4) improvement of disease signs and symptoms assessed by using the SCORAD index at 1 year of follow-up. Data were analyzed on an intention-to-treat basis. Results: At 1 year of follow-up, patients from the intervention group (n = 168) showed a significantly better improvement compared with the waiting group (n = 147) in the following defined primary study outcomes: coping behavior with respect to itching (P < .001), quality of life assessed by using the Skindex-29 questionnaire (P < .001), and the SCORAD index (P < .001). Conclusions: This is the first randomized, controlled multicenter study on patient education in adult AD. The ARNE training program shows significant beneficial effects on a variety of psychosocial parameters, as well as AD severity.
Metadaten zuletzt geändert: 25 Nov 2020 15:46
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