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An experimental and theoretical comparative study of the entrapment and release of dexamethasone from micellar and vesicular aggregates of PAMAM-PCL dendrimers

Avila-Salas, Fabián ; Pereira, Alfredo ; Rojas, Moisés A. ; Saavedra-Torres, Mario ; Montecinos, Rodrigo ; Bonardd, Sebastián ; Quezada, Caterina ; Saldías, Soledad ; Díaz Díaz, David ; Leiva, Angel ; Radic, Deodato ; Saldías, César


Self-assembling dendrimers in aqueous solution have attracted many efforts focused on the rationalization and development of consistent strategies to design carriers that are useful in the field of drug release. In this way, amphiphilic dendrimers with specific structural features and self-assembling behaviors in aqueous media would enable drug entrapment as well as drug release over a determined ...


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