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Improved risk stratification in prevention by use of a panel of selected circulating microRNAs

Keller, Till , Boeckel, Jes-Niels, Groß, Stefan, Klotsche, Jens, Palapies, Lars, Leistner, David , Pieper, Lars, Stalla, Günnter K., Lehnert, Hendrik, Silber, Sigmund, Pittrow, David, Maerz, Winfried, Dörr, Marcus, Wittchen, Hans-Ulrich, Baumeister, Sebastian E., Völker, Uwe, Felix, Stephan B., Dimmeler, Stefanie and Zeiher, Andreas M. (2017) Improved risk stratification in prevention by use of a panel of selected circulating microRNAs. Scientific Reports 7 (1).

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Other URL: http://doi.org/10.1038/s41598-017-04040-w

Dieser Artikel ist in einer Zeitschrift aus dem Directory of Open Access (DOAJ) publiziert.


Abstract

Risk stratification is crucial in prevention. Circulating microRNAs have been proposed as biomarkers in cardiovascular disease. Here a miR panel consisting of miRs related to different cardiovascular pathophysiologies, was evaluated to predict outcome in the context of prevention. MiR-34a, miR-223, miR-378, miR-499 and miR-133 were determined from peripheral blood by qPCR and combined to a risk ...

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Item type:Article
Date:2017
Institutions:Medicine > Institut für Epidemiologie und Präventivmedizin
Identification Number:
ValueType
10.1038/s41598-017-04040-wDOI
Keywords:ACUTE MYOCARDIAL-INFARCTION; C-REACTIVE PROTEIN; CARDIOVASCULAR-DISEASE; NONPARAMETRIC APPROACH; NATRIURETIC PEPTIDE; CARDIAC-HYPERTROPHY; SENSITIVE ASSAY; BIOMARKERS; PREDICTION; MORTALITY;
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:39379
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