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Prediabetes is associated with lower brain gray matter volume in the general population. The Study of Health in Pomerania (SHIP)

Markus, M.R.P. ; Ittermann, T. ; Wittfeld, K. ; Schipf, S. ; Siewert-Markus, U. ; Bahls, M. ; Bülow, R. ; Werner, N. ; Janowitz, D. ; Baumeister, S.E. ; Felix, S.B. ; Dörr, M. ; Rathmann, W. ; Völzke, H. ; Grabe, H.J.


Background and aims: We investigated the associations of fasting (FG) and 2h postload (2HG) plasma glucose from oral glucose tolerance test (OGTT) with gray (GMV) and white (WMV) matter volume. Methods and results: We analyzed data from 1330 subjects without known diabetes mellitus, aged 21 to 81, from the second cohort (SHIP-Trend-0) of the population-based Study of Health in Pomerania (SHIP). ...


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