Go to content
UR Home

Salt-responsive gut commensal modulates TH17 axis and disease

Wilck, Nicola ; Matus, Mariana G. ; Kearney, Sean M. ; Olesen, Scott W. ; Forslund, Kristoffer ; Bartolomaeus, Hendrik ; Haase, Stefanie ; Mähler, Anja ; Balogh, András ; Markó, Lajos ; Vvedenskaya, Olga ; Kleiner, Friedrich H. ; Tsvetkov, Dmitry ; Klug, Lars ; Costea, Paul I. ; Sunagawa, Shinichi ; Maier, Lisa ; Rakova, Natalia ; Schatz, Valentin ; Neubert, Patrick ; Frätzer, Christian ; Krannich, Alexander ; Gollasch, Maik ; Grohme, Diana A. ; Côrte-Real, Beatriz F. ; Gerlach, Roman G. ; Basic, Marijana ; Typas, Athanasios ; Wu, Chuan ; Titze, Jens M. ; Jantsch, Jonathan ; Boschmann, Michael ; Dechend, Ralf ; Kleinewietfeld, Markus ; Kempa, Stefan ; Bork, Peer ; Linker, Ralf A. ; Alm, Eric J. ; Müller, Dominik N.



Abstract

A Western lifestyle with high salt consumption can lead to hypertension and cardiovascular disease. High salt may additionally drive autoimmunity by inducing T helper 17 (T(H)17) cells, which can also contribute to hypertension. Induction of T(H)17 cells depends on gut microbiota; however, the effect of salt on the gut microbiome is unknown. Here we show that high salt intake affects the gut ...

plus


Owner only: item control page
  1. Homepage UR

University Library

Publication Server

Contact:

Publishing: oa@ur.de

Dissertations: dissertationen@ur.de

Research data: daten@ur.de

Contact persons