Go to content
UR Home

Chronic Inflammation Increases the Sensitivity of Mouse Treg for TNFR2 Costimulation

Schmid, Tobias ; Falter, Lena ; Weber, Sabine ; Müller, Nils ; Molitor, Konstantin ; Zeller, David ; Weber-Steffens, Dorothea ; Hehlgans, Thomas ; Wajant, Harald ; Mostböck, Sven ; Männel, Daniela N.


TNF receptor type 2 (TNFR2) has gained attention as a costimulatory receptor for T cells and as critical factor for the development of regulatory T cells (Treg) and myeloid suppressor cells. Using the TNFR2-specific agonist TNCscTNF80, direct effects of TNFR2 activation on myeloid cells and T cells were investigated in mice. In vitro, TNCscTNF80 induced T cell proliferation in a costimulatory ...


Owner only: item control page
  1. Homepage UR

University Library

Publication Server


Publishing: oa@ur.de
0941 943 -4239 or -69394

Dissertations: dissertationen@ur.de
0941 943 -3904

Research data: datahub@ur.de
0941 943 -5707

Contact persons