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1-Hz rTMS in the treatment of tinnitus: A sham-controlled, randomized multicenter trial

Landgrebe, Michael ; Hajak, Göran ; Wolf, Stefan ; Padberg, Frank ; Klupp, Philipp ; Fallgatter, Andreas J. ; Polak, Thomas ; Höppner, Jacqueline ; Haker, Rene ; Cordes, Joachim ; Klenzner, Thomas ; Schönfeldt-Lecuona, Carlos ; Kammer, Thomas ; Graf, Erika ; Koller, Michael ; Kleinjung, Tobias ; Lehner, Astrid ; Schecklmann, Martin ; Pöppl, Timm B. ; Kreuzer, Peter ; Frank, Elmar ; Langguth, Berthold


Background: Chronic tinnitus is a frequent, difficult to treat disease with high morbidity. Objective: This multicenter randomized, sham-controlled trial investigated the efficacy and safety of 1-Hz repetitive transcranial magnetic stimulation (rTMS) applied to the left temporal cortex in patients with chronic tinnitus. Methods: Tinnitus patients were randomized to receive 10 sessions of either ...


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