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Cycling CD34 expression in subpopulations of head and neck squamous cell carcinoma cell lines is involved in radioresistance and change in cytokeratin expression profile

Ettl, Tobias, Hautmann, Matthias, Reichert, Torsten E. and Bauer, Richard (2017) Cycling CD34 expression in subpopulations of head and neck squamous cell carcinoma cell lines is involved in radioresistance and change in cytokeratin expression profile. Clinical and Experimental Medicine 17 (4), pp. 565-574.

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Other URL: http://doi.org/10.1007/s10238-016-0440-3


Abstract

The expression of the hair follicle stem cell marker CD34 was analyzed in five different head and neck squamous cell carcinoma (HNSCC) cell lines with different antibodies. All HNSCC cell lines expressed CD34 on their cell surface. After cell cycle synchronization via serum starvation, we observed cyclic CD34 expression in HNSCC cells dependent on cell cycle progression via immunofluorescent ...

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Item type:Article
Date:2017
Institutions:Medicine > Lehrstuhl für Mund-, Kiefer- und Gesichtschirurgie
Medicine > Lehrstuhl für Strahlentherapie
Identification Number:
ValueType
10.1007/s10238-016-0440-3DOI
Keywords:COLONY-STIMULATING FACTOR; HAIR FOLLICLE BULGE; CANCER STEM-CELLS; KERATINOCYTES; RECURRENCE; PROGENITOR; RESISTANCE; APOPTOSIS; MELANOMA; TARGETS; CD34; Oral squamous cell carcinoma; Head and neck squamous cell carcinoma; Stem cell marker; Cell cycle; Differentiation; Keratinocyte
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:39630
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