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Implementation of a rapid HIT immunoassay at a university hospital – Retrospective analysis of HIT laboratory orders in patients with thrombocytopenia

Black, Anne ; Heimerl, Susanne ; Oertli, Linnéa ; Wilczek, Wolf ; Greinacher, Andreas ; Spannagl, Michael ; Herr, Wolfgang ; Hart, Christina



Abstract

Background: Heparin-induced thrombocytopenia (HIT) is a rare cause of thrombocytopenia and a potentially life-threatening adverse drug reaction. Clinical overdiagnosis of HIT results in costly laboratory tests and anticoagulation. Criteria and algorithms for diagnosis are established, but their translation into clinical practice is still challenging. Study design and methods: In a retrospective ...

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