Go to content
UR Home

CNV-association meta-analysis in 191,161 European adults reveals new loci associated with anthropometric traits

Macé, Aurélien, Tuke, Marcus A., Deelen, Patrick , Kristiansson, Kati, Mattsson, Hannele, Nõukas, Margit, Sapkota, Yadav , Schick, Ursula, Porcu, Eleonora, Rüeger, Sina, McDaid, Aaron F., Porteous, David, Winkler, Thomas W., Salvi, Erika, Shrine, Nick, Liu, Xueping, Ang, Wei Q., Zhang, Weihua, Feitosa, Mary F., Venturini, Cristina, van der Most, Peter J., Rosengren, Anders , Wood, Andrew R., Beaumont, Robin N., Jones, Samuel E., Ruth, Katherine S., Yaghootkar, Hanieh, Tyrrell, Jessica, Havulinna, Aki S., Boers, Harmen, Mägi, Reedik, Kriebel, Jennifer , Müller-Nurasyid, Martina, Perola, Markus, Nieminen, Markku, Lokki, Marja-Liisa, Kähönen, Mika , Viikari, Jorma S., Geller, Frank , Lahti, Jari , Palotie, Aarno, Koponen, Päivikki, Lundqvist, Annamari, Rissanen, Harri, Bottinger, Erwin P., Afaq, Saima, Wojczynski, Mary K., Lenzini, Petra, Nolte, Ilja M., Sparsø, Thomas, Schupf, Nicole, Christensen, Kaare , Perls, Thomas T. , Newman, Anne B., Werge, Thomas, Snieder, Harold, Spector, Timothy D., Chambers, John C., Koskinen, Seppo, Melbye, Mads, Raitakari, Olli T., Lehtimäki, Terho, Tobin, Martin D., Wain, Louise V., Sinisalo, Juha , Peters, Annette , Meitinger, Thomas, Martin, Nicholas G., Wray, Naomi R., Montgomery, Grant W. , Medland, Sarah E., Swertz, Morris A., Vartiainen, Erkki, Borodulin, Katja, Männistö, Satu, Murray, Anna, Bochud, Murielle, Jacquemont, Sébastien, Rivadeneira, Fernando, Hansen, Thomas F. , Oldehinkel, Albertine J., Mangino, Massimo, Province, Michael A., Deloukas, Panos, Kooner, Jaspal S., Freathy, Rachel M. , Pennell, Craig , Feenstra, Bjarke, Strachan, David P., Lettre, Guillaume, Hirschhorn, Joel, Cusi, Daniele, Heid, Iris M., Hayward, Caroline, Männik, Katrin, Beckmann, Jacques S. , Loos, Ruth J. F. , Nyholt, Dale R. , Metspalu, Andres, Eriksson, Johan G., Weedon, Michael N., Salomaa, Veikko, Franke, Lude, Reymond, Alexandre, Frayling, Timothy M. and Kutalik, Zoltán (2017) CNV-association meta-analysis in 191,161 European adults reveals new loci associated with anthropometric traits. Nature Communications 8 (1).

Full text not available from this repository.

at publisher (via DOI)

Other URL: http://doi.org/10.1038/s41467-017-00556-x

Dieser Artikel ist in einer Zeitschrift aus dem Directory of Open Access (DOAJ) publiziert.


Abstract

There are few examples of robust associations between rare copy number variants (CNVs) and complex continuous human traits. Here we present a large-scale CNV association meta-analysis on anthropometric traits in up to 191,161 adult samples from 26 cohorts. The study reveals five CNV associations at 1q21.1, 3q29, 7q11.23, 11p14.2, and 18q21.32 and confirms two known loci at 16p11.2 and 22q11.21, ...

plus


Export bibliographical data



Item type:Article
Date:2017
Institutions:Medicine > Institut für Epidemiologie und Präventivmedizin > Lehrstuhl für Genetische Epidemiologie
Identification Number:
ValueType
10.1038/s41467-017-00556-xDOI
Keywords:BODY-MASS INDEX; WILLIAMS-BEUREN-SYNDROME; GENOME-WIDE ASSOCIATION; DELETION SYNDROME; DEVELOPMENTAL DELAY; HUMAN HEIGHT; VARIANTS; OBESITY; SNP; MICRODUPLICATION;
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:39763
Owner only: item control page
  1. Homepage UR

University Library

Publication Server

Contact:

Publishing: oa@ur.de

Dissertations: dissertationen@ur.de

Research data: daten@ur.de

Contact persons