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Potential biomarkers to predict outcome of faecal microbiota transfer for recurrent Clostridioides difficile infection

Farowski, F. ; Solbach, P. ; Tsakmaklis, A. ; Brodesser, S. ; Cruz Aguilar, M. R. ; Cornely, O. A. ; Dettmer, Katja ; Higgins, P. G. ; Suerbaum, S. ; Jazmati, N. ; Oefner, Peter J. ; Vehreschild, M. J. G. T.



Abstract

Background & Aims: Faecal microbiota transplantation (FMT) has proven high clinical efficacy in the management of recurrent Clostridioides difficile infection (rCDI) with cure rates of over 80% after a single treatment. Nevertheless, the reasons for failure in the remaining 20% remain elusive. The aim of the present study was to investigate different potential predictors of response to FMT. ...

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