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Fulgimides as light-activated tools in biological investigations

Lachmann, Daniel ; Lahmy, Ranit ; König, Burkhard


With high spatiotemporal control, the conformation, rigidity and electronics of photoresponsive bioactive molecules can be altered. This, in turn, allows for control over the biological properties of these molecules. Incorporation of a photoswitchable moiety into a number of reported inhibitors, ligands and modulators has demonstrated the ability to modulate enzyme, receptor and ion channel ...


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