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Azologization of serotonin 5-HT3 receptor antagonists

Rustler, Karin , Maleeva, Galyna, Bregestovski, Piotr and König, Burkhard (2019) Azologization of serotonin 5-HT3 receptor antagonists. Beilstein Journal of Organic Chemistry 15, pp. 780-788.

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Date of publication of this fulltext: 02 Apr 2019 13:42

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Abstract

The serotonin 5-hydroxytryptamine 3 receptor (5-HT3R) plays a unique role within the seven classes of the serotonin receptor family, as it represents the only ionotropic receptor, while the other six members are G protein-coupled receptors (GPCRs). The 5-HT3 receptor is related to chemo-/radiotherapy provoked emesis and dysfunction leads to neurodevelopmental disorders and psychopathologies. ...

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Item type:Article
Date:2019
Institutions:Chemistry and Pharmacy > Institut für Organische Chemie > Lehrstuhl Prof. Dr. Burkhard König
Identification Number:
ValueType
10.3762/bjoc.15.74DOI
Keywords:azobenzene; 5-HT3R; ion currents; photopharmacology; serotonin
Dewey Decimal Classification:500 Science > 540 Chemistry & allied sciences
600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Partially
Item ID:40031
Owner only: item control page

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