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Oxidative stress-induced epigenetic transcriptional memory as a mechanism of programmed endothelial dysfunction in large for gestational age newborn of women with obesity

Carrasco Wong, Ivo (2019) Oxidative stress-induced epigenetic transcriptional memory as a mechanism of programmed endothelial dysfunction in large for gestational age newborn of women with obesity. PhD, Universität Regensburg.

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Date of publication of this fulltext: 25 Jun 2019 12:12

Abstract (English)

Obesity is a worldwide public health problem. Contrary to the general idea that the outcomes from an obesity state only affect to the individual, it is now clear that a direct association between maternal obesity and an increased cardiometabolic risks in the progeny. In several cardiovascular diseases, endothelial dysfunction is usually the earliest event present, much before hypertension can be ...

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Translation of the abstract (German)

Übergewicht ist ein weltweites Problem der öffentlichen Gesundheit. Entgegen der allgemeinen Vorstellung, dass die Ergebnisse eines Adipositaszustands nur den Einzelnen betreffen, ist nun klar, dass ein direkter Zusammenhang zwischen mütterlicher Adipositas und einem erhöhten kardiometabolischen Risiko bei den Nachkommen besteht. Bei mehreren Herz-Kreislauf-Erkrankungen ist die endotheliale ...

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Item type:Thesis of the University of Regensburg (PhD)
Date:25 June 2019
Referee:Prof. Dr. Paola Casanello
Date of exam:11 March 2019
Institutions:Biology, Preclinical Medicine > Institut für Biochemie, Genetik und Mikrobiologie > Lehrstuhl für Biochemie III > Prof. Dr. Gernot Längst
Keywords:Oxidative-stress, epigenetic, obesity
Dewey Decimal Classification:500 Science > 570 Life sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Partially
Item ID:40237
Owner only: item control page

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