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Identification of the retinoschisin-binding site on the retinal Na/K-ATPase

Ramchandran, Ramani, Plössl, Karolina, Straub, Kristina, Schmid, Verena, Strunz, Franziska, Wild, Jens, Merkl, Rainer, Weber, Bernhard H. F. and Friedrich, Ulrike (2019) Identification of the retinoschisin-binding site on the retinal Na/K-ATPase. PLOS ONE 14 (5), e0216320.

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Date of publication of this fulltext: 04 Jul 2019 04:51

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Other URL: http://doi.org/10.1371/journal.pone.0216320


X-linked juvenile retinoschisis (XLRS) is a hereditary retinal dystrophy, caused by mutations in the RS1 gene which encodes the secreted protein retinoschisin. In recent years, several molecules have been proposed to interact with retinoschisin, including the retinal Na/K-ATPase, L-voltage gated Ca2+ channels, and specific sugars. We recently showed that the retinal Na/K-ATPase consisting of ...


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Item type:Article
Date:2 May 2019
Institutions:Medicine > Lehrstuhl für Humangenetik
Projects:Open Access Publizieren (DFG)
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Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:40451
Owner only: item control page


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