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Improving preparedness to respond to cross-border hepatitis A outbreaks in the European Union/European Economic Area: towards comparable sequencing of hepatitis A virus

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Enkirch, Theresa ; Severi, Ettore ; Vennema, Harry ; Thornton, Lelia ; Dean, Jonathan ; Borg, Maria-Louise ; Ciccaglione, Anna Rita ; Bruni, Roberto ; Christova, Iva ; Ngui, Siew Lin ; Balogun, Koye ; Němeček, Vratislav ; Kontio, Mia ; Takács, Mária ; Hettmann, Andrea ; Korotinska, Rita ; Löve, Arthur ; Avellón, Ana ; Muñoz-Chimeno, Milagros ; de Sousa, Rita ; Janta, Denisa ; Epštein, Jevgenia ; Klamer, Sofieke ; Suin, Vanessa ; Aberle, Stephan W ; Holzmann, Heidemarie ; Mellou, Kassiani ; Ederth, Josefine Lundberg ; Sundqvist, Lena ; Roque-Afonso, Anne-Marie ; Filipović, Sanja Kurečić ; Poljak, Mario ; Vold, Line ; Stene-Johansen, Kathrine ; Midgley, Sofie ; Fischer, Thea Kølsen ; Faber, Mirko ; Wenzel, Jürgen J ; Takkinen, Johanna ; Leitmeyer, Katrin
License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 18 Jul 2019 13:23


Introduction: Sequence-based typing of hepatitis A virus (HAV) is important for outbreak detection, investigation and surveillance. In 2013, sequencing was central to resolving a large European Union (EU)-wide outbreak related to frozen berries. However, as the sequenced HAV genome regions were only partly comparable between countries, results were not always conclusive. Aim: The objective was to ...


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